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TFAP2D Antibody (PA5-100768) in ICC/IF
Immunocytochemistry analysis of TFAP2D in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with TFAP2D polyclonal antibody (Product # PA5-100768) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-100768
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TFAP2D(Accession Q7Z6R9), corresponding to amino acid residues D303-S353.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2850271
产品详细信息
Antibody detects endogenous levels of total TFAP2D.
靶标信息
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activating enhancer binding protein 2 beta-like 1; activating enhancer-binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP-2 like; AP2-delta; TFAP2D; transcription factor AP-2 beta (activating enhancer binding protein 2 beta)-like 1; transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)-like 1; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta
基因别名: Tcfap2d; TFAP2BL1; TFAP2D
UniProt ID: (Human) Q7Z6R9, (Mouse) Q91ZK0
Entrez Gene ID: (Human) 83741, (Rat) 301284, (Mouse) 226896
transcription, DNA-templated
regulation of cell proliferation
negative regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
anatomical structure development
inferior colliculus development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
