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Recommended positive controls: K562, HL-60.
Predicted reactivity: Mouse (89%), Rat (88%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC126368; TfR2; Transferrin receptor protein 2
基因别名: HFE3; TFR2; TFRC2
UniProt ID: (Human) Q9UP52
Entrez Gene ID: (Human) 7036