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产品信息
H00007041-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
4B2-D8
抗原
TGFB1I1 (AAH32545, 1 a.a. approximately 444 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MPRSGAPKER PAEPLTPPPS YGHQPQTGSG ESSGASGDKD HLYSTVCKPR SPKPAAPAAP PFSSSSGVLG TGLCELDRLL QELNATQFNI TDEIMSQFPS SKVASGEQKE DQSEDKKRPS LPSSPSPGLP KASATSATLE LDRLMASLSD FRVQNHLPAS GPTQPPVVSS TNEGSPSPPE PTGKGSLDTM LGLLQSDLSR RGVPTQAKGL CGSCNKPIAG QVVTALGRAW HPEHFVCGGC STALGGSSFF EKDGAPFCPE CYFERFSPRC GFCNQPIRHK MVTALGTHWH PEHFCCVSCG EPFGDEGFHE REGRPYCRRD FLQLFAPRCQ GCQGPILDNY ISALSALWHP DCFVCRECFA PFSGGSFFEH EGRPLCENHF HARRGSLCAT CGLPVTGRCV SALGRRFHPD HFTCTFCLRP LTKGSFQERA GKPYCQPCFL KLFG
靶标信息
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor coactivator 55 kDa protein; androgen receptor coactivator ARA55; Androgen receptor-associated protein of 55 kDa; Hic-5; Hydrogen peroxide-inducible clone 5 protein; hydrogen peroxide-inducible clone-5; Transforming growth factor beta-1-induced transcript 1 protein
基因别名: ARA55; HIC-5; HIC5; TGFB1I1; TSC-5
UniProt ID: (Human) O43294
Entrez Gene ID: (Human) 7041
transcription from RNA polymerase II promoter
cell adhesion
negative regulation of cell proliferation
response to heat
positive regulation of epithelial to mesenchymal transition
Wnt signaling pathway
morphogenesis of embryonic epithelium
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
androgen receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
epithelial cell differentiation
cell fate commitment
negative regulation of fat cell differentiation
positive regulation of transcription, DNA-templated
