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Positive Samples: BxPC-3, Mouse heart, Mouse kidney, Rat kidney; Cellular Location: extracellular matrix, extracellular space
Immunogen sequence: LPPRERSRLL GDAKELANIL KYHIGDEILV SGGIGALVRL KSLQGDKLEV SLKNNVVSVN KEPVAEPDIM ATNGVVHVIT NVLQPPANRP QERGDELADS A
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。