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TGR5 (GPBAR1) Antibody (ABR-031-200UL) in WB
Western blot analysis of rat brain (lanes 1 and 4), mouse liver (lanes 2 and 5) and rat spleen (lanes 3 and 6)lysates: - 1-3. Anti-TGR5 (GPBAR1) Antibody (#ABR-031), (1:200).4-6. Anti-TGR5 (GPBAR1) Antibody , preincubated with TGR5/GPBAR1 Blocking Peptide (#BLP-BR031).
产品信息
ABR-031-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)GDQRYTAPWRTAAQR, corresponding to amino acid residues 282-296 of rat GPBAR1, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor; G protein-coupled receptor TGR5; G-protein coupled bile acid receptor 1; GPCR HBG37; M-BAR; membrane bile acid receptor; Membrane-type receptor for bile acids
基因别名: BG37; Gpbar1; GPCR; GPR131; M-BAR; TGR5
UniProt ID: (Rat) Q80T02, (Mouse) Q80SS6
Entrez Gene ID: (Rat) 338443, (Mouse) 227289
