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THRAP3/TRAP150 Antibody (A300-956A) in IHC (P)
Detection of human THRAP3/TRAP150 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-THRAP3/TRAP150 (Product # A300-956A) (Lot 2) used at a dilution of 1:200 (1 µg/mL). Detection: DAB.
产品信息
A300-956A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 905 and the C-terminus (residue 955) of Human Thyroid Hormone Receptor Associated Protein 3 (Thyroid Hormone Receptor-Asscociated Protein, 150 kDa).
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
THRAP3 is a 955 amino acid novel nuclear receptor and a member of the Thyroid hormone receptor associated proteins with a LISH domain and no obvious known sequence motifs. THRAP3 is a 150 kDa subunit of the large multiprotein complex TRAP and is important in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It is also known to play an important role in transcriptional coactivation. It is known to interact with DKC1, nop5/nap65 and fibrillarin. From the Northern blot analysis of several human tissues it was found that TRAP150 is ubiquitously expressed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCLAF1 and THRAP3 family member 2; Thyroid hormone receptor-associated protein 3; Thyroid hormone receptor-associated protein complex 150 kDa component; thyroid hormone receptor-associated protein, 150 kDa subunit; Trap150
基因别名: BCLAF2; THRAP3; TRAP150
UniProt ID: (Human) Q9Y2W1
Entrez Gene ID: (Human) 9967
core promoter sequence-specific DNA binding
RNA polymerase II transcription cofactor activity
transcription cofactor activity
transcription coactivator activity
receptor activity
protein binding
ATP binding
ligand-dependent nuclear receptor transcription coactivator activity
vitamin D receptor binding
poly(A) RNA binding
thyroid hormone receptor binding
phosphoprotein binding
nucleic acid metabolism protein
regulation of alternative mRNA splicing, via spliceosome
nuclear-transcribed mRNA catabolic process
transcription initiation from RNA polymerase II promoter
mRNA processing
circadian rhythm
RNA splicing
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of circadian rhythm
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of mRNA splicing, via spliceosome
mRNA stabilization
