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Recommended positive controls: A431, HeLa.
Predicted reactivity: Mouse (90%), Rat (88%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 30 kDa HIV-1 TAT-interacting protein; FLJ26963; HIV-1 tat interactive protein 2, 30 kDa homolog; HIV-1 Tat interactive protein 2, 30kDa; HIV-1 TAT-interactive protein 2; HTATIP2; Oxidoreductase HTATIP2; short chain dehydrogenase/reductase family 44U, member 1; Tat-interacting protein (30kD); tat-interacting protein 30 kDa
基因别名: AW111545; CC3; HTATIP2; SDR44U1; TIP30
UniProt ID: (Human) Q9BUP3, (Mouse) Q9D5F8
Entrez Gene ID: (Human) 10553, (Mouse) 53415