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TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; DDF1; DKFZP434J214; DKFZp686N0351; DKFZp686P1838; FLJ40466; PARP-1; PARP-7; Poly [ADP-ribose] polymerase 7; Protein mono-ADP-ribosyltransferase TIPARP; TCDD-inducible poly [ADP-ribose] polymerase; TCDD-inducible poly(ADP-ribose) polymerase
基因别名: ARTD14; PARP7; pART14; TIPARP
UniProt ID: (Human) Q7Z3E1
Entrez Gene ID: (Human) 25976