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Peptide sequence: GSSSGLLALG ALGSQAHLTV KDEKNHHELD HRERESSANN SVSPSESLRA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 79%
The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: enhancer of split groucho 3; Enhancer of split groucho-like protein 3; ESG-1; ESG-2; ESG-3; ESG-4; ESG3; Tle1; Tle2; tle4; transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 3 short isoform; transducin-like enhancer of split 3, homolog of Drosophila E(sp1); Transducin-like enhancer protein 3
基因别名: ESG; ESG3; GRG3; HsT18976; KIAA1547; TLE3
UniProt ID: (Human) Q04726
Entrez Gene ID: (Human) 7090