Invitrogen

TMEM106B Polyclonal Antibody

TMEM106B Antibody in Immunohistochemistry (IHC)

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TMEM106B Antibody (PA5-34353) in IHC

Immunohistochemistry of TMEM106B in human liver tissue with TMEM106B Polyclonal Antibody (Product # PA5-34353) at 2.5 µg/mL.

TMEM106B Antibody in Western Blot, Immunoprecipitation (WB, IP)

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产品信息

PA5-34353

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

查看2篇已发表文章 2篇已发表文章

免疫组化 (IHC)

2.5 µg/mL

免疫沉淀 (IP)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A 15 amino acid synthetic peptide near the amino terminus of human TMEM106B

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2551705

产品详细信息

A suggested positive control is human liver tissue lysate.

PA5-34353 can be used with blocking peptide PEP-1396.

靶标信息

Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence.

F1000Research

Ayoubi R,Fotouhi M,Southern K,Bhajiawala R,Fanti R,Prinos P,McPherson PS,Laflamme C

Published figure using TMEM106B polyclonal antibody (Product # PA5-34353) in Western Blot

Tue Aug 08 00:00:00 UTC 2023

The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence.

F1000Research

Ayoubi R,Fotouhi M,Southern K,Bhajiawala R,Fanti R,Prinos P,McPherson PS,Laflamme C

Published figure using TMEM106B polyclonal antibody (Product # PA5-34353) in Western Blot

Tue Aug 08 00:00:00 UTC 2023

Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations.

eNeuro

Holler CJ,Taylor G,Deng Q,Kukar T

PA5-34353 was used in Western Blotting to report the identification and characterisation of antibodies that reliably detect several human GRNs by immunoblot and immunocytochemistry.

Thu May 03 00:00:00 UTC 2018

Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations.

eNeuro

Holler CJ,Taylor G,Deng Q,Kukar T

PA5-34353 was used in Western Blotting to report the identification and characterisation of antibodies that reliably detect several human GRNs by immunoblot and immunocytochemistry.