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产品信息
PA5-60072
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648683
产品详细信息
Immunogen sequence: IKFELDIEPK VFKPPSSTEA LNDSQEFPFP ETPTKVWPQD EYIVEYSLEY GFLRLSQATR QRLSIPVMVV TL
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.
靶标信息
Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas.
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生物信息学
蛋白别名: aspecific BCL2 ARE-binding protein 1; Membralin; Transmembrane protein 259
基因别名: ASBABP1; C19orf6; MBRL; MEMBRALIN; R32184_3; TMEM259
UniProt ID: (Human) Q4ZIN3
Entrez Gene ID: (Human) 91304
