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产品信息
PA5-20915
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 14 amino acid peptide near the center of human TMEM70.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11155419
产品详细信息
A suggested positive control is human liver tissue lysate.
PA5-20915 can be used with blocking peptide PEP-1029.
靶标信息
TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
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生物信息学
蛋白别名: Transmembrane protein 70, mitochondrial
基因别名: 1110020A09Rik; 2210416J16Rik; MC5DN2; RGD1566224; TMEM70
UniProt ID: (Human) Q9BUB7, (Mouse) Q921N7
Entrez Gene ID: (Human) 54968, (Mouse) 70397, (Rat) 500384
