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TMEM70 Antibody (PA5-89378) in WB
Western blot analysis of TMEM70 in extracts of HeLa cells. Samples were incubated with TMEM70 Polyclonal antibody (Product # PA5-89378) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-89378
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 161-260 of human TMEM70 (NP_0603363)
偶联物
形式
Liquid
浓度
0.72 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805534
产品详细信息
Immunogen sequence: FITKGYVIRL YHEATTDTYK AITYNAMLAE TSTVFHQNDV KIPDAKHVFT TFYAKTKSLL VNPVLFPNRE DYIHLMGYDK EEFILYMEET SEEKRHKDDK; Positive Samples: HeLa; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein
靶标信息
TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Transmembrane protein 70, mitochondrial
基因别名: 1110020A09Rik; 2210416J16Rik; MC5DN2; TMEM70
UniProt ID: (Human) Q9BUB7, (Mouse) Q921N7
Entrez Gene ID: (Human) 54968, (Mouse) 70397
