Product References
Tenascin-C fibronectin D domain is involved in the fine-tuning of glial response to CNS injury in vitro.
Frontiers in cell and developmental biology
Bijelić D,Adžić M,Perić M,Reiss G,Milošević M,Andjus PR,Jakovčevski I
13-7341-81 was used in Enzyme-linked immunosorbent assay to show versatile functions of TnC and in particular FnD after injury, mostly contributing to ongoing inflammation in the injury region.
Tue Sep 13 00:00:00 UTC 2022
Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response.
International journal of molecular sciences
Milosevic K,Stevanovic I,Bozic ID,Milosevic A,Janjic MM,Laketa D,Bjelobaba I,Lavrnja I,Savic D
13-7341-81 was used in ELISA to show that agmatine suppresses nitrosative and oxidative burst in Lps-stimulated microglia by reducing iNOS and XO activity and decreasing O2- levels, arresting lipid peroxidation, increasing total glutathione content, and preserving GR and CAT activity.
Thu Mar 24 00:00:00 UTC 2022
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Immunity
Xian H,Liu Y,Rundberg Nilsson A,Gatchalian R,Crother TR,Tourtellotte WG,Zhang Y,Aleman-Muench GR,Lewis G,Chen W,Kang S,Luevanos M,Trudler D,Lipton SA,Soroosh P,Teijaro J,de la Torre JC,Arditi M,Karin M,Sanchez-Lopez E
13-7341-81 was used in ELISA to conclude that inhibition of ATP and mtDNA synthesis is sufficient for ARDS amelioration.
Tue Jul 13 00:00:00 UTC 2021
Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co-culture.
The European journal of neuroscience
Frühauf M,Zeitschel U,Höfling C,Ullm F,Rabiger FV,Alber G,Pompe T,Müller U,Roßner S
13-7341 was used in an ELISA assay to indicate that biomimetic 3D matrices allow for co-cultivation and activation of primary microglia and T cells and provide useful tools to study their interaction in vitro.
Tue Jun 01 00:00:00 UTC 2021
Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip.
eLife
Muri J,Thut H,Feng Q,Kopf M
Published figure using TNF alpha polyclonal antibody (Product # 13-7341-81) in ELISA
Tue Feb 25 00:00:00 UTC 2020
Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high dose.
Redox biology
Muri J,Wolleb H,Broz P,Carreira EM,Kopf M
13-7341 was used in an ELISA assay to find that exposure of bone marrow-derived dendritic cells (BMDCs) to low concentrations of a variety of electrophilic Nrf2 activators including itaconate prior to Toll-like receptor (TLR) stimulation inhibits transcription of pro-inflammatory cytokines (such as interleukin [IL]-12 and IL-1β) by activation of Nrf2.
Tue Sep 01 00:00:00 UTC 2020
GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance.
Cell
Luan HH,Wang A,Hilliard BK,Carvalho F,Rosen CE,Ahasic AM,Herzog EL,Kang I,Pisani MA,Yu S,Zhang C,Ring AM,Young LH,Medzhitov R
13-7341 was used in an ELISA assay to show that GDF15 coordinates tolerance to inflammatory damage through regulation of triglyceride metabolism.
Thu Aug 22 00:00:00 UTC 2019
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
Cell metabolism
Sanchez-Lopez E,Zhong Z,Stubelius A,Sweeney SR,Booshehri LM,Antonucci L,Liu-Bryan R,Lodi A,Terkeltaub R,Lacal JC,Murphy AN,Hoffman HM,Tiziani S,Guma M,Karin M
13-7341 was used in ELISA to conclude that choline kinase inhibitors ameliorated acute and chronic models of IL-1β-dependent inflammation.
Tue Jun 04 00:00:00 UTC 2019
Extracellular vesicles deliver Mycobacterium RNA to promote host immunity and bacterial killing.
EMBO reports
Cheng Y,Schorey JS
13-7341 was used in an ELISA assay to hypothesize that EVs, which are preferentially removed by macrophages in vivo, can be combined with effective antibiotics as a novel approach to treat drug-resistant TB.
Fri Mar 01 00:00:00 UTC 2019
Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation.
Scientific reports
Dai D,Yuan J,Wang Y,Xu J,Mao C,Xiao Y
Published figure using TNF alpha polyclonal antibody (Product # 13-7341-81) in ELISA
Wed May 29 00:00:00 UTC 2019
Mycobacterium tuberculosis-induced IFN-β production requires cytosolic DNA and RNA sensing pathways.
The Journal of experimental medicine
Cheng Y,Schorey JS
Published figure using TNF alpha polyclonal antibody (Product # 13-7341-81) in ELISA
Mon Nov 05 00:00:00 UTC 2018
Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication.
Cell host & microbe
Maruzuru Y,Ichinohe T,Sato R,Miyake K,Okano T,Suzuki T,Koshiba T,Koyanagi N,Tsuda S,Watanabe M,Arii J,Kato A,Kawaguchi Y
13-7341-81 was used in ELISA to reveal a mechanism of HSV-1 evasion of the host immune response that enables efficient viral replication in vivo.
Wed Feb 14 00:00:00 UTC 2018
Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation.
Cell
Wang A,Huen SC,Luan HH,Yu S,Zhang C,Gallezot JD,Booth CJ,Medzhitov R
13-7341 was used in an ELISA assay to analyse the effects of anorxia in mouse models wih viral and bacterial infections.
Thu Sep 08 00:00:00 UTC 2016
Interferon-gamma and nitric oxide synthase 2 mediate the aggregation of resident adherent peritoneal exudate cells: implications for the host response to pathogens.
PloS one
Chandrasekar BS,Yadav S,Victor ES,Majumdar S,Deobagkar-Lele M,Wadhwa N,Podder S,Das M,Nandi D
13-7341 was used in an ELISA assay to elucidate novel roles for Ifnγ and Nos2 in regulating Actin, Tubulin, CD11b, motility and morphology during APEC aggregation responses.
Tue Apr 12 00:00:00 UTC 2016
The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E.
PloS one
Namjoshi DR,Martin G,Donkin J,Wilkinson A,Stukas S,Fan J,Carr M,Tabarestani S,Wuerth K,Hancock RE,Wellington CL
13-7341 was used in an ELISA assay to investigate the therapeutic use of Liver X receptor for treatment of TBI.
Tue Jul 09 00:00:00 UTC 2013