Product References
Nanomaterials-Mediated Co-Stimulation of Toll-Like Receptors and CD40 for Antitumor Immunity.
Advanced materials (Deerfield Beach, Fla.)
Yan J,Zhang Y,Du S,Hou X,Li W,Zeng C,Zhang C,Cheng J,Deng B,McComb DW,Zhao W,Xue Y,Kang DD,Cheng X,Dong Y
14-7325-81 was used in Enzyme-linked immunosorbent assay to develop an immunotherapy regimen that enables co-stimulation of TLR7/8- and CD40-mediated pathways.
Tue Nov 01 00:00:00 UTC 2022
Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation.
Scientific reports
Dai D,Yuan J,Wang Y,Xu J,Mao C,Xiao Y
Published figure using TNF alpha monoclonal antibody (Product # 14-7325-81) in ELISA
Wed May 29 00:00:00 UTC 2019
RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.
PLoS pathogens
Ates LS,Sayes F,Frigui W,Ummels R,Damen MPM,Bottai D,Behr MA,van Heijst JWJ,Bitter W,Majlessi L,Brosch R
14-7325 was used in an ELISA assay to show that a predicted total of 89 PE_PGRS/PPE-MPTR surface proteins are not exported by certain animal-adapted strains of the M. tuberculosis complex including M. bovis.
Fri Jun 01 00:00:00 UTC 2018
Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties.
Scientific reports
Leroux LP,Nasr M,Valanparambil R,Tam M,Rosa BA,Siciliani E,Hill DE,Zarlenga DS,Jaramillo M,Weinstock JV,Geary TG,Stevenson MM,Urban JF,Mitreva M,Jardim A
14-7325 was used in an ELISA assay to analyse the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties.
Mon Oct 29 00:00:00 UTC 2018
Orally administered sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice.
Experimental and therapeutic medicine
Ono K,Nimura S,Hideshima Y,Nabeshima K,Nakashima M
14-7325 was used in an ELISA assay to investigate the effects of orally administered sodium 4-phenylbutyrate in mice.
Fri Dec 01 00:00:00 UTC 2017
Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF.
Nature communications
Wang X,Chen H,Tian R,Zhang Y,Drutskaya MS,Wang C,Ge J,Fan Z,Kong D,Wang X,Cai T,Zhou Y,Wang J,Wang J,Wang S,Qin Z,Jia H,Wu Y,Liu J,Nedospasov SA,Tredget EE,Lin M,Liu J,Jiang Y,Wu Y
14732581 was used in immunohistochemistry - frozen section to propose that macrophage-TNF-induced AKT/beta-catenin signaling in Lgr5(+) hair follicle stem cells is important for promoting hair follicle cycling and neogenesis after wounding
Mon Mar 27 00:00:00 UTC 2017
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection.
PLoS pathogens
Sayes F,Pawlik A,Frigui W,Gröschel MI,Crommelynck S,Fayolle C,Cia F,Bancroft GJ,Bottai D,Leclerc C,Brosch R,Majlessi L
Fri Jul 01 00:00:00 UTC 2016
Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.
Nature communications
Ulland TK,Jain N,Hornick EE,Elliott EI,Clay GM,Sadler JJ,Mills KA,Janowski AM,Volk AP,Wang K,Legge KL,Gakhar L,Bourdi M,Ferguson PJ,Wilson ME,Cassel SL,Sutterwala FS
14-7325 was used in an ELISA assay to demonstrate that C57BL/6J mice have a functional defect in NLRP12, which is required by macrophages for effective neutrophil recruitment to inflammatory sites.
Tue Oct 25 00:00:00 UTC 2016
SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression.
Nature communications
Shao L,Zhou HJ,Zhang H,Qin L,Hwa J,Yun Z,Ji W,Min W
Published figure using TNF alpha monoclonal antibody (Product # 14-7325-81) in ELISA
Tue Nov 24 00:00:00 UTC 2015
Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury.
Journal of neuroinflammation
Haan N,Zhu B,Wang J,Wei X,Song B
Sat May 30 00:00:00 UTC 2015
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
Nature medicine
Komatsu N,Okamoto K,Sawa S,Nakashima T,Oh-hora M,Kodama T,Tanaka S,Bluestone JA,Takayanagi H
14-7325-81 was used in T-Cell Activation to establish the pathological importance of Foxp3 instability in the generation of pathogenic TH17 cells in autoimmunity.
Wed Jan 01 00:00:00 UTC 2014
Neisseria gonorrhoeae induces a tolerogenic phenotype in macrophages to modulate host immunity.
Mediators of inflammation
Escobar A,Candia E,Reyes-Cerpa S,Villegas-Valdes B,Neira T,Lopez M,Maisey K,Tempio F,Ríos M,Acuña-Castillo C,Imarai M
14-7325 was used in an ELISA assay to determine whether N. gonorrhoeae directly conditions the phenotype of RAW 264.7 murine macrophage cell line and its response.
Thu Jun 05 00:00:00 UTC 2014
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.
Journal of immunology (Baltimore, Md. : 1950)
Nijnik A,Clare S,Hale C,Chen J,Raisen C,Mottram L,Lucas M,Estabel J,Ryder E,Adissu H,Adams NC,Ramirez-Solis R,White JK,Steel KP,Dougan G,Hancock RE
14-7325 was used in an ELISA assay to study the roles of Spns2 in mammals and its involvement in the different S1P-dependent physiological processes.
Sun Jul 01 00:00:00 UTC 2012
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Nature immunology
Levy D,Kuo AJ,Chang Y,Schaefer U,Kitson C,Cheung P,Espejo A,Zee BM,Liu CL,Tangsombatvisit S,Tennen RI,Kuo AY,Tanjing S,Cheung R,Chua KF,Utz PJ,Shi X,Prinjha RK,Lee K,Garcia BA,Bedford MT,Tarakhovsky A,Cheng X,Gozani O
14-7325 was used in an ELISA assay to screen candidate protein lysine methyltransferases and identify SETD6 as a methyltransferase that monomethylated chromatin-associated transcription factor NF-κB subunit RelA.
Sat Jan 01 00:00:00 UTC 2011
Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.
Journal of immunology (Baltimore, Md. : 1950)
Nijnik A,Madera L,Ma S,Waldbrook M,Elliott MR,Easton DM,Mayer ML,Mullaly SC,Kindrachuk J,Jenssen H,Hancock RE
14-7325 was used in an ELISA assay to study the importance of the chemokine induction activity of host defence peptides in protection against bacterial infections.
Mon Mar 01 00:00:00 UTC 2010
Approaches to determine expression of inflammatory cytokines.
Methods in molecular biology (Clifton, N.J.)
Amsen D,de Visser KE,Town T
14-7325 was used in an ELISA assay to describe a protocol for quantification of cytokine mRNA.
Mon May 18 00:00:00 UTC 2009
Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus.
Journal of virology
Castilow EM,Olson MR,Meyerholz DK,Varga SM
14-7325 was used in an ELISpot assay to compare the immune response elicited by the G versus F protein of the respiratory syncytial virus, showing a differential role of gamma interferon.
Sat Mar 01 00:00:00 UTC 2008