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产品信息
PA5-120969
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 950-1050 of human TNRC6A (NP_055309.2).
偶联物
形式
Liquid
浓度
0.57 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914541
产品详细信息
Positive test controls include: Mouse brain, Rat brain. The target is usually found in the following locations: Cytoplasm, P-body.
Immunogen sequence: QDIVGSWGIP PATGKPPGTG WLGGPIPAPA KEEEPTGWEE PSPESIRRKM EIDDGTSAWG DPSKYNYKNV NMWNKNVPNG NSRSDQQAQV HQLLTPASAI S
靶标信息
TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAG repeat protein 26; CTD-2540M10.1; DKFZp666E117; EDIE; EMSY interactor protein; FLJ22043; Glycine-tryptophan protein of 182 kDa; GW182 autoantigen; MGC75384; Protein GW1; trinucleotide repeat containing 6; Trinucleotide repeat-containing gene 6A protein
基因别名: 2010321I05Rik; 3110054G10Rik; AW557223; CAGH26; D130023A07Rik; GW1; GW182; KIAA1460; TNRC6; TNRC6A
UniProt ID: (Human) Q8NDV7, (Mouse) Q3UHK8
Entrez Gene ID: (Human) 27327, (Rat) 308971, (Mouse) 233833
Wnt signaling pathway, calcium modulating pathway
gene silencing by RNA
posttranscriptional gene silencing by RNA
gene silencing by miRNA
miRNA mediated inhibition of translation
phosphatidylinositol-mediated signaling
biological_process
cellular response to starvation
regulation of translation
maintenance of protein location in cell
