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产品信息
PA5-20443
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 17 amino acid peptide near the carboxy terminus of the human TOCA-1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152974
产品详细信息
A suggested positive control is mouse brain tissue lysate.
PA5-20443 can be used with blocking peptide PEP-0560.
靶标信息
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cdc42 effector; formin binding protein 1-like; Formin-binding protein 1-like; Toca-1; transducer of Cdc42-dependent actin assembly 1; Transducer of Cdc42-dependent actin assembly protein 1
基因别名: 2610318I01Rik; AW548221; C1orf39; FNBP1L; RGD1305386; Toca-1; TOCA1
UniProt ID: (Human) Q5T0N5, (Rat) Q2HWF0
Entrez Gene ID: (Human) 54874, (Rat) 310839, (Mouse) 214459
membrane budding
autophagy
membrane invagination
vesicle organization
vesicle transport along actin filament
cilium assembly
positive regulation of GTPase activity
positive regulation of filopodium assembly
clathrin-mediated endocytosis
membrane tubulation
cell-cell adhesion
endocytosis
nervous system development
cell differentiation
