Invitrogen

TOP1 Monoclonal Antibody (K94015_6C5)

TOP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TOP1 Antibody (MA5-55869) in IHC (P)

Immunohistochemistry analysis of TOP1 in paraffin-embedded tonsil tissue. Sample was incubated with TOP1 monoclonal antibody (Product # MA5-55869) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temperature. The ... View More

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产品信息

MA5-55869

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1.0 µg/mL

免疫组化（石蜡） (IHC (P))

5.0 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

K94015_6C5

抗原

Recombinant human TOP1 (immunogen range is 221-420).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

产品详细信息

Sequence of this protein is as follows: EHKGPVFAPP YEPLPENVKF YYDGKVMKLS PKAEEVATFF AKMLDHEYTT KEIFRKNFFK DWRKEMTNEE KNIITNLSKC DFTQMSQYFK AQTEARKQMS KEEKLKIKEE NEKLLKEYGF CIMDNHKERI ANFKIEPPGL FRGRGNHPKM GMLKRRIMPE DIIINCSKDA KVPSPPPGHK WKEVRHDNKV TWLVSWTENI

靶标信息

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

仅用于科研。不用于诊断过程。未经明确授权不得转售。