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产品信息
MA5-34785
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JG38-66
抗原
Recombinant protein within Human Tropomyosin 1 aa 168-284
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
RRID
AB_2848693
产品详细信息
Positive Control: Rat heart tissue, rat smooth muscle tissue, human heart tissue, mouse skeletal muscle tissue, MCF-7.
靶标信息
Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-tropomyosin; cardiomyopathy, hypertrophic 3; epididymis secretory protein Li 265; sarcomeric tropomyosin kappa; TPM1-alpha; tropomyosin; Tropomyosin alpha-1 chain; Tropomyosin-1
基因别名: C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TMSA; TPM1
UniProt ID: (Human) P09493
Entrez Gene ID: (Human) 7168
in utero embryonic development
positive regulation of heart rate by epinephrine
movement of cell or subcellular component
muscle contraction
regulation of muscle contraction
cytoskeleton organization
regulation of heart contraction
regulation of cell shape
muscle filament sliding
negative regulation of cell migration
ruffle organization
positive regulation of ATPase activity
cellular response to reactive oxygen species
wound healing
sarcomere organization
positive regulation of cell adhesion
positive regulation of stress fiber assembly
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
negative regulation of vascular smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell migration
