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产品信息
PA5-43143
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human TPM2 (aa 235-284).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2609629
产品详细信息
Peptide sequence: AETRAEFAER SVAKLEKTID DLEDEVYAQK MKYKAISEEL DNALNDITSL
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 79%; Horse: 85%; Human: 100%; Mouse: 100%; Pig: 85%; Rabbit: 100%; Rat: 100%; Sheep: 85%; Zebrafish: 86%
靶标信息
TPM2 (tropomyosin 2) is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers. TPM2 binds to actin filaments in muscle and non-muscle cells. Plays a central role in association with the troponin complex in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Mutations in this gene can cause nemaline myopathy 4, arthrogryposis dital 1A/2B, and cap myopathy 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-tropomyosin; epididymis secretory protein Li 273; nemaline myopathy type 4; RP11-112J3.4; tropomyosin; Tropomyosin beta chain; Tropomyosin-2
基因别名: AMCD1; DA1; DA2B; HEL-S-273; NEM4; TMSB; TPM2
UniProt ID: (Human) P07951
Entrez Gene ID: (Human) 7169
