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产品信息
PA5-54049
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648856
产品详细信息
Immunogen sequence: RDEEVSSADI SSSSEVISQH LVSYRNIEEL QQQNQRLLVA LRELGETRER EEQETTSSKI TELQLKLESA LTELEQLRKS RQHQMQLVDS IVRQRDMYRI LLSQTTGVAI PLHASSLDDV SLASTPKRPS TSQTVSTPAP
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
靶标信息
Steroidogenic factor-1 (SF-1) regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. In the adult ovary, SF-1 localizes to theca/interstitial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; Nucleoprotein TPR; translocated promoter region (to activated MET oncogene); Translocated promoter region protein; tumor potentiating region
基因别名: TPR
UniProt ID: (Human) P12270
Entrez Gene ID: (Human) 7175
molecular_function
chromatin binding
mRNA binding
transporter activity
nucleocytoplasmic transporter activity
protein binding
tubulin binding
heat shock protein binding
protein homodimerization activity
protein anchor
poly(A) RNA binding
mitogen-activated protein kinase binding
dynein complex binding
primary active transporter
negative regulation of transcription from RNA polymerase II promoter
MAPK import into nucleus
RNA import into nucleus
RNA export from nucleus
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
protein export from nucleus
nuclear pore organization
mitotic nuclear division
mitotic nuclear envelope disassembly
mitotic spindle assembly checkpoint
biological_process
regulation of mRNA export from nucleus
regulation of glucose transport
regulation of mitotic sister chromatid separation
viral process
protein sumoylation
viral transcription
gene silencing by RNA
positive regulation of heterochromatin assembly
regulation of protein stability
mRNA export from nucleus in response to heat stress
cellular response to heat
cellular response to interferon-alpha
regulation of protein import into nucleus
positive regulation of protein import into nucleus
nuclear matrix organization
negative regulation of translational initiation
regulation of protein export from nucleus
positive regulation of protein export from nucleus
negative regulation of RNA export from nucleus
nuclear pore complex assembly
cell division
response to epidermal growth factor
intracellular transport of virus
positive regulation of mitotic cell cycle spindle assembly checkpoint
positive regulation of intracellular protein transport
regulation of cellular response to heat
regulation of mitotic spindle assembly
