Invitrogen

TPR Polyclonal Antibody

查看其他17个TPR抗体
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说明书
实验方案
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产品信息

PA5-95533

应用
建议稀释比
已发表文章

免疫印迹 (WB)

0.1-0.5 µg/mL
-

免疫组化（石蜡） (IHC (P))

0.5-1 µg/mL
-

免疫组化（冰冻） (IHC (F))

0.5-1 µg/mL
-

免疫细胞化学 (ICC/IF)

2 µg/mL
-

流式细胞分析 (Flow)

1-3 µg/1x10^6 cells
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence of human TPR (MLQAEKKLLEEDVKRWKARNQHLVSQQKD).
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

纯化类型

Affinity chromatography

保存液

PBS with 4mg trehalose

内含物

0.05mg sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2807335

产品详细信息

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

靶标信息

Steroidogenic factor-1 (SF-1) regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. In the adult ovary, SF-1 localizes to theca/interstitial cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; Nucleoprotein TPR; translocated promoter region (to activated MET oncogene); Translocated promoter region and nuclear basket protein; Translocated promoter region protein; tumor potentiating region

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基因别名: 2610029M07Rik; C77892; TPR

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UniProt ID: (Human) P12270, (Mouse) F6ZDS4

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Entrez Gene ID: (Human) 7175, (Mouse) 108989, (Rat) 304862

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功能
molecular_function chromatin binding mRNA binding transporter activity nucleocytoplasmic transporter activity protein binding tubulin binding heat shock protein binding protein homodimerization activity protein anchor poly(A) RNA binding mitogen-activated protein kinase binding dynein complex binding primary active transporter
参与通路
negative regulation of transcription from RNA polymerase II promoter MAPK import into nucleus RNA import into nucleus RNA export from nucleus mRNA export from nucleus tRNA export from nucleus protein import into nucleus protein export from nucleus nuclear pore organization mitotic nuclear division mitotic nuclear envelope disassembly mitotic spindle assembly checkpoint biological_process regulation of mRNA export from nucleus regulation of glucose transport regulation of mitotic sister chromatid separation viral process protein sumoylation viral transcription gene silencing by RNA positive regulation of heterochromatin assembly regulation of protein stability mRNA export from nucleus in response to heat stress cellular response to heat cellular response to interferon-alpha regulation of protein import into nucleus positive regulation of protein import into nucleus nuclear matrix organization negative regulation of translational initiation regulation of protein export from nucleus positive regulation of protein export from nucleus negative regulation of RNA export from nucleus nuclear pore complex assembly cell division response to epidermal growth factor intracellular transport of virus positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of intracellular protein transport regulation of cellular response to heat regulation of mitotic spindle assembly transport cell cycle protein transport mRNA transport
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