Invitrogen

TRAK2 Polyclonal Antibody

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TRAK2 Antibody (PA5-21858) in WB

Western Blot using TRAK2 Polyclonal Antibody (Product # PA5-21858). Sample (30 µg of whole cell lysate). A: Hep G2. B: Molt-4. 7.5% SDS PAGE. TRAK2 Polyclonal Antibody (Product # PA5-21858) diluted at 1:1,000.

TRAK2 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

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产品信息

PA5-21858

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

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免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to a region within amino acids 852 and 914 of TRAK2 (Uniprot ID#O60296)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_11155420

产品详细信息

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.

Predicted reactivity: Rhesus Monkey (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells.

Frontiers in cellular neuroscience

Quintanilla RA,Tapia-Monsalves C,Vergara EH,Pérez MJ,Aranguiz A

PA5-21858 was used in Western Blot, Immunocytochemistry to study the possible role of motor proteins (kinesin 1 and dynein) and mitochondrial protein adaptors (RhoT1/T2, syntaphilin, and TRAK2) in the mitochondrial transport failure induced by caspase-cleaved tau.

Mon Sep 28 00:00:00 UTC 2020

Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells.

Frontiers in cellular neuroscience

Quintanilla RA,Tapia-Monsalves C,Vergara EH,Pérez MJ,Aranguiz A

Mon Sep 28 00:00:00 UTC 2020

Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells.

Frontiers in cellular neuroscience

Quintanilla RA,Tapia-Monsalves C,Vergara EH,Pérez MJ,Aranguiz A

Mon Sep 28 00:00:00 UTC 2020

Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells.

Frontiers in cellular neuroscience

Quintanilla RA,Tapia-Monsalves C,Vergara EH,Pérez MJ,Aranguiz A

Mon Sep 28 00:00:00 UTC 2020

生物信息学

蛋白别名: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein; EMBL AAH60681.1; gamma-aminobutyric acid(A) receptor-interacting factor; milton homolog 2; O-linked N-acetylglucosamine transferase interacting protein 98; Trafficking kinesin-binding protein 2; trafficking protein, kinesin binding 2

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基因别名: ALS2CR3; CALS-C; GRIF-1; GRIF1; KIAA0549; MILT2; OIP98; TRAK2

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UniProt ID: (Human) O60296

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Entrez Gene ID: (Human) 66008

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功能

receptor binding protein binding enzyme binding GABA receptor binding membrane traffic protein

参与通路

regulation of transcription from RNA polymerase II promoter protein O-linked glycosylation protein targeting