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Peptide sequence: CPFDRQVTDL GDSGVWGLKK NFALLELLER LQNGPIGQYG AAEESIGISG
Sequence homology: Cow: 90%; Guinea Pig: 85%; Horse: 85%; Human: 100%; Mouse: 85%; Rabbit: 85%; Rat: 91%
Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; ARF domain protein 1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; RING finger protein 46; RING-type E3 ubiquitin transferase TRIM23; tripartite motif protein TRIM23; tripartite motif-containing 23; Tripartite motif-containing protein 23
基因别名: ARD1; ARFD1; RNF46; TRIM23
UniProt ID: (Human) P36406
Entrez Gene ID: (Human) 373