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TRIM37 Antibody (PA5-110519) in WB
Western blot analysis of TRIM37 in extracts of various cell lines. Samples were incubated with TRIM37 Polyclonal antibody (Product # PA5-110519) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-110519
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 735-964 of human TRIM37 (NP_0010052071)
偶联物
形式
Liquid
浓度
1.24 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855930
产品详细信息
Immunogen sequence: LGMELLAKSS VANCYIRNST NKKSNSPKPA RSSVAGSLSL RRAVDPGENS RSKGDCQTLS EGSPGSSQSG SRHSSPRALI HGSIGDILPK TEDRQCKALD SDAVVVAVFS GLPAVEKRRK MVTLGANAKG GHLEGLQMTD LENNSETGEL QPVLPEGASA APEEGMSSDS DIECDTENEE QEEHTSVGGF HDSFMVMTQP PDEDTHSSFP DGEQIGPEDL SFNTDENSGR
靶标信息
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase TRIM37; RING-type E3 ubiquitin transferase TRIM37; TRAF encompassing factor 3; tripartite motif protein 37; Tripartite motif-containing protein 37
基因别名: 1110032A10Rik; 2810004E07Rik; AI848587; AU043018; Kiaa0898; mKIAA0898; MUL; TEF3; Trim37
UniProt ID: (Mouse) Q6PCX9
Entrez Gene ID: (Mouse) 68729, (Rat) 360592
chromatin binding
ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
ubiquitin protein ligase binding
protein homodimerization activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
molecular_function
ubiquitin-protein ligase
protein modifying enzyme
negative regulation of transcription from RNA polymerase II promoter
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
biological_process
