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产品信息
MA5-19380
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2D11
抗原
TRIM37 (NP_056109, 865 a.a. ~ 964 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609952
产品详细信息
Peptide Sequence: GHLEGLQMTD LENNSETGEL QPVLPEGASA APEEGMSSDS DIECDTENEE QEEHTSVGGF HDSFMVMTQP PDEDTHSSFP DGEQIGPEDL SFNTDENSGR
靶标信息
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase TRIM37; Mulibrey nanism protein; RING-B-box-coiled-coil protein; RING-type E3 ubiquitin transferase TRIM37; Tripartite motif-containing protein 37
基因别名: KIAA0898; MUL; POB1; TEF3; TRIM37
UniProt ID: (Human) O94972
Entrez Gene ID: (Human) 4591
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
