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Recommended positive controls: HepG2, 3XFlag-human TRIM8-transfected 293T.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (91%), Cat (100%), Chicken (94%), Rhesus Monkey (100%), Bovine (100%).
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase TRIM8; glioblastoma expressed ring finger protein; Glioblastoma-expressed RING finger protein; RING finger protein 27; RING-type E3 ubiquitin transferase TRIM8; tripartite motif protein TRIM8; tripartite motif-containing 8; Tripartite motif-containing protein 8
基因别名: GERP; RNF27; TRIM8
UniProt ID: (Human) Q9BZR9
Entrez Gene ID: (Human) 81603