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产品信息
MA1-23294
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
10G5
抗原
Amino acids 1099-1372 of Trip230 expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2209356
产品详细信息
Recommended positive controls: MCF7, HBL100, T24.
靶标信息
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Clonal evolution-related gene on chromosome 14 protein; GMAP-210; Golgi-associated microtubule-binding protein 210; Golgi-microtubule-associated protein of 210 kDa; Thyroid receptor-interacting protein 11; TR-interacting protein 11; Trip230
基因别名: ACG1A; CEV14; GMAP-210; GMAP210; TRIP-11; TRIP11; TRIP230
UniProt ID: (Human) Q15643
Entrez Gene ID: (Human) 9321
