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TRPC1 Antibody (PA5-100358) in ICC/IF
Immunofluorescent analysis of TRPC1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and TRPC1 polyclonal antibody (Product # PA5-100358) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-100358
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TRPC1(Accession P48995), corresponding to amino acid residues I695-S745.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849871
产品详细信息
Antibody detects endogenous levels of total TRPC1.
靶标信息
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: capacitative calcium channel protein Trp1; Short transient receptor potential channel 1; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; Transient receptor protein 1; TRP-1; Trp-related protein 1; TrpC1
基因别名: HTRP-1; Mtrp1; TRP1; TRPC1; Trrp1
UniProt ID: (Human) P48995, (Mouse) Q61056, (Rat) Q9QX01
Entrez Gene ID: (Human) 7220, (Mouse) 22063, (Rat) 89821
calcium ion transport
manganese ion transport
melanin biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
response to calcium ion
calcium ion transmembrane transport
cellular response to hypoxia
regulation of cardiac conduction
transport
ion transport
saliva secretion
transmembrane transport
cation transmembrane transport
