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TRPC1 (extracellular) Antibody (ACC-118-200UL) in ICC/IF
Expression of TRPC1 in PC12 cells - Cell surface detection of TRPC1 in intact living PC12 cells. A. Extracellular staining of cells with Anti-TRPC1 (extracellular) Antibody (#ACC-118), (1:50) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody . B. Nuclear staining with DAPI as the counterstain. C. Merged images of A and B.
产品信息
ACC-118-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)SMGQMLQDFGK, corresponding to amino acid residues 495-505 of rat TRPC1, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: capacitative calcium channel protein Trp1; Short transient receptor potential channel 1; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; Transient receptor protein 1; TRP-1; Trp-related protein 1; TrpC1
基因别名: HTRP-1; Mtrp1; TRP1; TRPC1; Trrp1
UniProt ID: (Human) P48995, (Mouse) Q61056, (Rat) Q9QX01
Entrez Gene ID: (Human) 7220, (Mouse) 22063, (Rat) 89821
calcium ion transport
manganese ion transport
melanin biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
response to calcium ion
calcium ion transmembrane transport
cellular response to hypoxia
regulation of cardiac conduction
transport
ion transport
saliva secretion
transmembrane transport
cation transmembrane transport
