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TRPM7 (extracellular) Polyclonal Antibody

TRPM7 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

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TRPM7 (extracellular) Antibody (ACC-129-200UL) in IHC (F)

Expression of TRPM7 in rat hippocampus. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-TRPM7 (extracellular) Antibody (#ACC-129), (1:600), followed by goat Anti-rabbit-AlexaFluor-488. A. Staining in the rat hippocampal dentate gyrus, showed TRPM7 immunoreactivity (green) in neurons (arrows). B. Pre-incubation of the Antibody with TRPM7 (extracellular) Blocking Peptide (B... View More

TRPM7 (extracellular) Antibody in Western Blot (WB)

TRPM7 (extracellular) Antibody in Flow Cytometry (Flow)

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产品信息

ACC-129-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（冰冻） (IHC (F))

1:600

流式细胞分析 (Flow)

2.5 µg

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)RFGAKWNYINAYDNH, corresponding to amino acid residues 942-956 of mouse TRPM7, Extracellular, 2nd loop

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).

靶标信息

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Channel kinase 1; Channel-kinase 1; FLJ20117; Long transient receptor potential channel 7; long transient receptor potential channel 7 {ECO:0000250|UniProtKB:Q96QT4}; LTRPC ion channel family member 7; LTrpC-7; LTrpC7 {ECO:0000250|UniProtKB:Q96QT4}; tr; Transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7 {ECO:0000312|RGD:620053}; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential M7; Transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-phospholipase C-interacting kinase {ECO:0000303|PubMed:11161216}; transient receptor potential-related protein, ChaK; TRMP7; TRP PLIK; TRP-PLIK; TRP-PLIK {ECO:0000303|PubMed:11161216}; trpm7 {ECO:0000312|RGD:620053}

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基因别名: 2310022G15Rik; 4833414K03Rik; 5033407O22Rik; ALSPDC; CHAK; CHAK1; Ltpr7; LTrpC-7; LTRPC7; TRP-PLIK; TRPM7; TRPPLIK

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UniProt ID: (Human) Q96QT4, (Mouse) Q925B2

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Entrez Gene ID: (Human) 54822, (Mouse) 58800, (Rat) 679906

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功能