Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 4
TSN Antibody (PA5-116869) in IHC (P)
Immunohistochemistry analysis of TSN in paraffin-embedded human colon carcinoma. Samples were incubated with TSN Polyclonal antibody (Product # PA5-116869) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116869
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_0046131)
偶联物
形式
Liquid
浓度
1.72 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901500
产品详细信息
Positive Samples: K-562, HeLa, Mouse spleen, Mouse brain, Rat thymus, Rat spleen
Immunogen sequence: GFQDIPKRCL KAREHFGTVK THLTSLKTKF PAEQYYRFHE HWRFVLQRLV FLAAFVVYLE TETLVTREAV TEILGIEPDR EKGFHLDVED YLSGVLILAS E
靶标信息
Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: C3PO; Component 3 of promoter of RISC; recombination hotspot associated factor; recombination hotspot-binding protein; TB-RBP; testis brain-RNA binding protein; Testis/brain RNA-binding protein; testis/brain-RNA-binding protein; Translin
基因别名: 2610034C24Rik; AU040286; BCLF-1; C3PO; RCHF1; REHF-1; TB-RBP; TBRBP; TRSLN; TSN
UniProt ID: (Human) Q15631, (Mouse) Q62348
Entrez Gene ID: (Human) 7247, (Rat) 60381, (Mouse) 22099
DNA binding
mRNA binding
endonuclease activity
protein binding
sequence-specific DNA binding
single-stranded DNA binding
RNA binding
endoribonuclease activity
protein complex binding
nuclease activity
hydrolase activity
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
