Invitrogen

TTLL11 Polyclonal Antibody

图: 1 / 2

TTLL11 Antibody (PA5-46070) in WB

Western blot analysis of human THP-1 cell lysate using an anti-TTLL11 polyclonal antibody (Product # PA5-46070).

TTLL11 Antibody in Immunocytochemistry (ICC/IF)

Product Image Gallery

产品信息

PA5-46070

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the N-terminal of human TTLL11 (aa 169-218).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2606522

产品详细信息

Peptide sequence: QVLQRPPPTL PPSKPKPVQG LCPHGKPRDK GRSCKRSSGH GSGENGSQRP

Sequence homology: Human: 100%; Rabbit: 92%

靶标信息

TTLL11 is a polyglutamase which preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. TTLL11 is required for CCSAP localization to both spindle and cilia microtubules.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family.

Scientific reports

Mathieu H,Patten SA,Aragon-Martin JA,Ocaka L,Simpson M,Child A,Moldovan F

PA5-46070 was used in Immunocytochemistry to identify an insertion in the tubulin tyrosine ligase like gene as the causative gene of idiopathic scoliosis in a British family.

Wed May 26 00:00:00 UTC 2021

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family.

Scientific reports

Mathieu H,Patten SA,Aragon-Martin JA,Ocaka L,Simpson M,Child A,Moldovan F

PA5-46070 was used in Immunocytochemistry to identify an insertion in the tubulin tyrosine ligase like gene as the causative gene of idiopathic scoliosis in a British family.

Wed May 26 00:00:00 UTC 2021

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family.

Scientific reports

Mathieu H,Patten SA,Aragon-Martin JA,Ocaka L,Simpson M,Child A,Moldovan F

PA5-46070 was used in Immunocytochemistry to identify an insertion in the tubulin tyrosine ligase like gene as the causative gene of idiopathic scoliosis in a British family.

Wed May 26 00:00:00 UTC 2021

生物信息学

蛋白别名: Tubulin polyglutamylase TTLL11; tubulin tyrosine ligase like11; tubulin tyrosine ligase-like family member 11; tubulin tyrosine ligase-like family, member 11; Tubulin--tyrosine ligase-like protein 11

查看更多收起

基因别名: bA244O19.1; C9orf20; TTLL11

查看更多收起

UniProt ID: (Human) Q8NHH1

查看更多收起

Entrez Gene ID: (Human) 158135

查看更多收起

功能

ATP binding ligase activity microtubule or microtubule-binding cytoskeletal protein

参与通路

protein polyglutamylation microtubule severing