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产品信息
MA5-25018
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI4B2
抗原
Full length human recombinant protein of TTLL12 produced in HEK293T cell
偶联物
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723743
靶标信息
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Inactive tubulin--tyrosine ligase-like protein 12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12
基因别名: dJ526I14.2; KIAA0153; RGD1305319; TTLL12
UniProt ID: (Human) Q14166
Entrez Gene ID: (Human) 23170, (Rat) 300105
