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Recommended positive controls: NT2D1, PC-3.
Predicted reactivity: Mouse (98%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4. Also acts as a monoglutamylase: generates monoglutamylation of CGAS, leading to impair the nucleotidyltransferase activity of CGAS. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein monoglutamylase TTLL4; Tubulin monoglutamylase TTLL4; tubulin tyrosine ligase-like family member 4; tubulin tyrosine ligase-like family, member 4; Tubulin--tyrosine ligase-like protein 4
基因别名: KIAA0173; TTLL4
UniProt ID: (Human) Q14679
Entrez Gene ID: (Human) 9654