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产品信息
PA5-55500
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2649097
产品详细信息
Immunogen sequence: DGLEDCCSRD ENEEEEGDSE CSSLSAVSPS ESVAMISRSC MEILTKPLSN HEKVVRPALI YSLFPNVPPT IYFGTRDERV EKLPWEQRKL LRWKMSTVTP NIVKQTIGRS HFKISKRNDD WLGCWGHHMK SPSFRSI
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
靶标信息
Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4. Also acts as a monoglutamylase: generates monoglutamylation of CGAS, leading to impair the nucleotidyltransferase activity of CGAS. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein monoglutamylase TTLL4; Tubulin monoglutamylase TTLL4; tubulin tyrosine ligase-like family member 4; tubulin tyrosine ligase-like family, member 4; Tubulin--tyrosine ligase-like protein 4
基因别名: KIAA0173; TTLL4
UniProt ID: (Human) Q14679
Entrez Gene ID: (Human) 9654
