Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
H00007274-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
7B5
抗原
TTPA (NP_000361.1, 179 a.a. approximately 278 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: IAAVLTDSFP LKVRGIHLIN EPVIFHAVFS MIKPFLTEKI KERIHMHGNN YKQSLLQHFP DILPLEYGGE EFSMEDICQE WTNFIMKSED YLSSISESIQ
靶标信息
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Alpha-tocopherol transfer protein; Alpha-TTP; tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)
基因别名: alphaTTP; ATTP; AVED; TPP1; TTP1; TTPA
UniProt ID: (Human) P49638
Entrez Gene ID: (Human) 7274
embryonic placenta development
lipid metabolic process
transport
response to nutrient
response to pH
response to toxic substance
vitamin E metabolic process
intermembrane transport
vitamin transport
intracellular pH reduction
negative regulation of cell death
negative regulation of establishment of blood-brain barrier
