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Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, Neuro2A, GL261.
Predicted reactivity: Mouse (92%), Rat (93%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: retinal degeneration 5; tubby homolog; tubby homologue; Tubby protein; Tubby protein homolog
基因别名: Rd5; RDOB; TUB
UniProt ID: (Human) P50607, (Mouse) P50586, (Rat) O88808
Entrez Gene ID: (Human) 7275, (Mouse) 22141, (Rat) 25609