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Peptide sequence: DSLASVQLGA TRPTAPASAK RTKAAATAGG QGGAARKEKK GKHKGTSGPA
Sequence homology: Dog: 92%; Guinea Pig: 85%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: tubby homolog; tubby homologue; Tubby protein homolog
基因别名: rd5; RDOB; TUB
UniProt ID: (Human) P50607
Entrez Gene ID: (Human) 7275