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Immunogen sequence: LASPQSLPPAS PLLEDREEGD LGKASELAET PKEEKAEGAA MLELVGSILR GCVPGVYRVQ TVPSARRPVV KFCHRPSGLH GD
Highest antigen sequence identity to the following orthologs - mouse 81%, rat 80%.
TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA (RNU6; MIM 180692) and is essential for cell proliferation (Trippe et al., 2006 [PubMed 16790842]).[supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ21850; FLJ22267; FLJ22347; MGC131987; MGC149809; nuclear speckle targeted phosphatidylinositol 4-phosphate 5-kinase type I-alpha regulated-poly(A) polymerase; nuclear speckle-targeted PIPK1A-regulated-poly(A) polymerase; PAP-associated domain-containing 2; poly(A) polymerase associated domain containing 2; RNA binding motif protein 21; RNA uridylyltransferase; RNA-binding motif protein 21; RNA-binding protein 21; Speckle targeted PIP5K1A-regulated poly(A) polymerase; Star-PAP; terminal uridylyl transferase 1 U6 snRNA-specific; TUTase 6; U6 snRNA-specific terminal uridylyltransferase 1; U6 TUTase; U6-TUTase; up-regulated in lung cancer 6
基因别名: PAPD2; RBM21; STARPAP; TUT1; TUTase; URLC6
UniProt ID: (Human) Q9H6E5
Entrez Gene ID: (Human) 64852