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TXNIP Antibody (PA5-49279) in IHC (P)
Immunohistochemistry analysis of TXNIP in paraffin-embedded Mouse liver tissue. Samples were incubated with TXNIP polyclonal antibody (Product # PA5-49279) using a dilution of 1:100 for 1 hour at room temperature followed by undiluted CRF Anti-Polyvalent HRP Polymer antibody. Tissue was fixed with formaldehyde at room temperature. Heat induced epitope retrieval was performed by EDTA buffer (pH 9 0).
产品信息
PA5-49279
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2634734
产品详细信息
Predicted to react with rat based on sequence homology.
靶标信息
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hyperlipidemia 1; thioredoxin binding protein-2; Thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; Vitamin D3 up-regulated protein 1
基因别名: 1200008J08Rik; AA682105; Hyplip1; Tbp-2; THIF; Txnip; VDUP1
UniProt ID: (Mouse) Q8BG60
Entrez Gene ID: (Mouse) 56338
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
protein import into nucleus
response to oxidative stress
cell cycle
keratinocyte differentiation
regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of catalytic activity
platelet-derived growth factor receptor signaling pathway
negative regulation of cell division
cellular response to tumor cell
