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Recommended positive controls: 293T, A431, H1299, HeLaS3.
Predicted reactivity: Mouse (88%), Rat (89%), Pig (88%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2
基因别名: IMD35; JTK1; TYK2
UniProt ID: (Human) P29597
Entrez Gene ID: (Human) 7297