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Taurine Transporter (SLC6A6) Antibody (AGT-006-200UL) in WB
Western blot analysis of human HL-60 promyelocytic leukemia cell lysate (lanes 1 and 3) and human HT-29 colon adenocarcinoma cell lysate (lanes 2 and 4): - 1,2. Anti-Taurine Transporter (SLC6A6) Antibody (#AGT-006), (1:200).3,4. Anti-Taurine Transporter (SLC6A6) Antibody , preincubated with Taurine Transporter/SLC6A6 Blocking Peptide (#BLP-GT006).
Product Details
AGT-006-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)TPREPNRWAVEREG, corresponding to amino acid residues 581-594 of rat TauT, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier 6 ,member 6 (taurine transporter); solute carrier family 6 (neurotransmitter transporter, taurine), member 6; Solute carrier family 6 member 6; solute carrier family 6, member 6; Taurine Transporter; taurine/beta-alanine transporter
Gene Aliases: AA589629; C80501; SLC6A6; TAUT
UniProt ID: (Human) P31641, (Mouse) O35316, (Rat) P31643
Entrez Gene ID: (Human) 6533, (Mouse) 21366, (Rat) 29464
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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