NeoBiotechnologies

Thrombomodulin/CD141 Recombinant Mouse Monoclonal Antibody (rTHBD, 1591)

Thrombomodulin/CD141 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Thrombomodulin/CD141 Antibody (7056-MSM3-P1ABX) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human cervical carcinoma using Thrombomodulin, CD141 Recombinant Monoclonal Antibody (Product # 7056-MSM3-P1ABX).

Thrombomodulin/CD141 Antibody in Peptide array (ARRAY)

Thrombomodulin/CD141 Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

7056-MSM3-P1ABX

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

肽阵列 (Array)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

rTHBD, 1591

抗原

Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Antibody is tested in direct ELISA (Use Ab at 2-4 µg/mL for coating.

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

仅用于科研。不用于诊断过程。未经明确授权不得转售。