Invitrogen

Thrombospondin 1 Polyclonal Antibody

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Thrombospondin 1 Antibody in Immunohistochemistry (IHC)

Thrombospondin 1 Antibody in Immunohistochemistry (IHC)

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Thrombospondin 1 Antibody (PA1-29196) in IHC

Pulmonary circulation 2013 - Published figure using Thrombospondin 1 polyclonal antibody (Product # PA1-29196) in Immunohistochemistry

Thrombospondin 1 Antibody in Immunohistochemistry (IHC)

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Thrombospondin 1 Antibody in Immunohistochemistry (IHC) — Published figure using Thrombospondin 1 polyclonal antibody (Product # PA1-29196) in Immunohistochemistry

产品信息

PA1-29196

应用

建议稀释比

已发表文章

免疫印迹 (WB)

5-10 µg/mL

-

免疫组化 (IHC)

-

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免疫细胞化学 (ICC/IF)

Assay-dependent

-

免疫沉淀 (IP)

10 µg/mg protein lysate

-

产品规格

种属反应

Bovine, Human, Mouse

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Purified human platelet TSP

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.2, with 0.2% BSA

内含物

0.09% sodium azide

保存条件

4° C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

AB_2303216

产品详细信息

Positive Control: HUVEC Cells

靶标信息

Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.

Pulmonary circulation

Rogers NM,Yao M,Sembrat J,George MP,Knupp H,Ross M,Sharifi-Sanjani M,Milosevic J,St Croix C,Rajkumar R,Frid MG,Hunter KS,Mazzaro L,Novelli EM,Stenmark KR,Gladwin MT,Ahmad F,Champion HC,Isenberg JS

Published figure using Thrombospondin 1 polyclonal antibody (Product # PA1-29196) in Immunofluorescence

Sun Dec 01 00:00:00 UTC 2013

生物信息学

蛋白别名: Glycoprotein G; Thrombospondin-1; thrombospondin-1p180; thrombospondin-p50; ThrombospondinTHBS1

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基因别名: BOS_10716; tbsp1; THBS; THBS-1; THBS1; TSP; TSP-1; TSP1

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UniProt ID: (Human) P07996, (Bovine) Q28178

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Entrez Gene ID: (Human) 7057, (Bovine) 281530, (Mouse) 21825

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phosphatidylserine binding glycoprotein binding fibronectin binding integrin binding calcium ion binding protein binding heparin binding fibroblast growth factor binding low-density lipoprotein particle binding identical protein binding laminin binding proteoglycan binding transforming growth factor beta binding fibrinogen binding collagen V binding extracellular matrix binding

activation of MAPK activity response to hypoxia negative regulation of endothelial cell proliferation negative regulation of cell-matrix adhesion sprouting angiogenesis chronic inflammatory response platelet degranulation negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II negative regulation of dendritic cell antigen processing and presentation inflammatory response immune response response to unfolded protein cell cycle arrest cell adhesion response to glucose positive regulation of endothelial cell migration negative regulation of endothelial cell migration negative regulation of plasma membrane long-chain fatty acid transport negative regulation of nitric oxide mediated signal transduction negative regulation of cGMP-mediated signaling negative regulation of plasminogen activation positive regulation of macrophage chemotaxis positive regulation of fibroblast migration cell migration negative regulation of angiogenesis peptide cross-linking positive regulation of blood coagulation extracellular matrix organization positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway regulation of cGMP metabolic process response to magnesium ion response to progesterone negative regulation of interleukin-12 production positive regulation of transforming growth factor beta1 production cellular response to heat response to endoplasmic reticulum stress protein O-linked fucosylation negative regulation of fibroblast growth factor receptor signaling pathway positive regulation of phosphorylation response to drug positive regulation of tumor necrosis factor biosynthetic process positive regulation of macrophage activation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration engulfment of apoptotic cell positive regulation of translation positive regulation of angiogenesis behavioral response to pain positive regulation of chemotaxis response to calcium ion negative regulation of focal adhesion assembly positive regulation of protein kinase B signaling negative regulation of fibrinolysis positive regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of endothelial cell apoptotic process positive regulation of reactive oxygen species metabolic process negative regulation of endothelial cell chemotaxis negative regulation of extrinsic apoptotic signaling pathway outflow tract morphogenesis endocardial cushion development growth plate cartilage development response to mechanical stimulus positive regulation of cell-substrate adhesion blood vessel morphogenesis positive regulation of transforming growth factor beta production cellular response to nitric oxide