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NeoBiotechnologies
Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Rabbit Monoclonal Antibody (TOP1MT, 2883R)
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Topoisomerase I, Mitochondrial (TOP1MT) Antibody (116447-RBM4-P1ABX) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreas using Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Monoclonal Antibody (Product # 116447-RBM4-P1ABX).
产品信息
116447-RBM4-P1ABX
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
TOP1MT, 2883R
抗原
Recombinant full-length human TOP1MT protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA topoisomerase I; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase IB; TOP1M; TOP1mt; Topoisomerase I mitochondrial; Type IB Topoisomerase
基因别名: TOP1MT
UniProt ID: (Human) Q969P6
Entrez Gene ID: (Human) 116447
