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NeoBiotechnologies
Topoisomerase I, Mitochondrial (TOP1MT) Monoclonal Antibody (TOP1MT/488)
产品信息
116447-MSM1-P0
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
TOP1MT/488
抗原
Recombinant full-length human TOP1MT protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA topoisomerase I; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase IB; TOP1M; TOP1mt; Topoisomerase I mitochondrial; Type IB Topoisomerase
基因别名: TOP1MT
UniProt ID: (Human) Q969P6
Entrez Gene ID: (Human) 116447
