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产品信息
PA5-29729
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 17 and 233 of Human Torsin-1A
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547203
产品详细信息
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (91%), Rat (91%), Pig (93%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; dystonia 1, torsion (autosomal dominant; torsin A); Torsin 1A; torsin A; torsin ATPase 1; Torsin ATPase-1A; Torsin family 1 member A; torsin family 1, member A (torsin A); Torsin-1A
基因别名: DQ2; DYT1; TA; TOR1A; TORA
UniProt ID: (Human) O14656
Entrez Gene ID: (Human) 1861
protein deneddylation
response to oxidative stress
organelle organization
nuclear envelope organization
cell adhesion
neuron projection development
protein localization to nucleus
wound healing, spreading of cells
intermediate filament cytoskeleton organization
synaptic vesicle transport
chaperone mediated protein folding requiring cofactor
protein homooligomerization
regulation of dopamine uptake involved in synaptic transmission
chaperone-mediated protein folding
ER-associated misfolded protein catabolic process
nuclear membrane organization
chaperone-mediated protein transport
positive regulation of synaptic vesicle endocytosis
regulation of protein localization to cell surface
