Invitrogen

Transferrin Receptor Monoclonal Antibody (R17217.1.4), FITC

Transferrin Receptor Antibody in Flow Cytometry (Flow)

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Transferrin Receptor Antibody (MA5-17922) in Flow

Flow cytometric analysis of HLA-DR Mouse Hybridomas staining using anti-CD71/transferrin receptor Monoclonal Antibody (Product # MA5-17922) at a 1.0 µg/10^6 cells dilution. The Isotypic control was a FITC Rat IgG2a

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产品信息

MA5-17922

应用

建议稀释比

已发表文章

免疫组化 (IHC)

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流式细胞分析 (Flow)

1.0 µg/1x10^6 cells

产品规格

种属反应

Mouse

已发表种属

Not Applicable

宿主/亚型

Rat / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

R17217.1.4

抗原

Friend erythroleukemia 745.6 induced for 5 days in 1.5% dimethyl sulfoxide.

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偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Protein G

保存液

PBS with 4-5mg/mL BSA

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

运输条件

Ambient (domestic); Wet ice (international)

AB_2539306

产品详细信息

MA5-17922 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples.

靶标信息

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。