Search Thermo Fisher Scientific
Recommended positive controls: 293T, A431, H1299, HeLaS3, Molt-4, Raji, NIH-3T3.
Predicted reactivity: Mouse (91%), Rat (91%), Pig (96%), Chicken (81%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。